This is going to be really, really brief on Prototype 2.|
The first game was pretty enjoyable, though the "aftergame" isn't so much. I was actually tempted to start a New Game+, and still might someday.
However, Prototype 2 made me sit through a full hour of cutscenes and quicktime-type events (Hold R2 and run for 5 minutes in one direction?) before it let me get to any actual gameplay. That's pretty shoddy and not looking up for the game's prospects. Oh, and by the time the cutscenes finished they'd taken the entire advertised character motivation and inverted it. Way to quicken and cheapen a story.