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Alzheimer's actually Diabetes?

Articles / Personal Stuff/Random News
Date: Oct 02, 2007 - 10:00 AM
Science Daily has news on an intriguing discovery - Alzheimer's, the disease that causes memory problems with advanced age, may actually be a form of diabetes.

Insulin isn't just used for sugar regulation - it's also an important brain signal.

"We found the binding of ADDLs to synapses somehow prevents insulin receptors from accumulating at the synapses where they are needed," said William L. Klein, professor of neurobiology and physiology in the Weinberg College of Arts and Sciences, who led the research team. "Instead, they are piling up where they are made, in the cell body, near the nucleus. Insulin cannot reach receptors there. This finding is the first molecular evidence as to why nerve cells should become insulin resistant in Alzheimer's disease."




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